pt. 1. The healthy breast 1. The breast and its development The ductal anatomy How the breast develops 2. Getting acquainted with your breasts 3. Variations in development and plastic surgery Variations apparent at birth Variations appearing a puberty Plastic surgery Thinking about plastic surgery pt. 2. Common problems 4. "Fibrocystic disease" and breast pain Cyclical pain Noncyclical pain Nonbreast-origin pain 5. Breast infections and nipple problems Breast infections : intrinsic Breast infections : extrinsic Infection and cancer Nipple problems 6. Lumps and lumpiness Cysts Fibroadenomas Pseudolumps Cancer What to do if you think you have a lump pt. 3. Diagnosis of breast problems 7. Diagnostic imaging : mammography, ultrasound, MRI, and other techniques Mammograms Quality of mammograms Ultrasound MRI PET scanning MIBI scan CT scanning Thermography Other techniques The future 8. Biopsy Fine-needle biopsy Core biopsy Surgical biopsy How to read your biopsy report pt. 4. Prediction, prevention, and screening 9. Risk factors : nongenetic Observational studies Understanding risk Hormonal risk factors Fertility drugs Pesticides and other environmental hazards Diet Alcohol consumption Radiation Occupational exposures Electromagnetic field (EMF) exposure 10. Risk factors : genetic BRCA 1 and 2 Testing Choices Pulling it together 11. Prevention Diet Exercise Hormones Tamoxifen and other SERMs Other potential chemoprevention strategies Preventive surgery The future 12. Precancerous conditions Lobular cancer in situ Ductal carcinoma in situ 13. The intraductal approach : getting to the source 14. Screening Evaluating screening tests Breast self-exam Breast physical exam Mammography Screening recommendations

pt. 5. Diagnosis of breast cancer and decisions 15. Introduction to breast cancer Statistics Treatment studies : clinical trials and research protocols Becoming part of a study 16. What kind of cancer is it? How to interpret a pathology report Staging Biomarkers Combined markers 17. Treatment options : local therapy Surgery and radiation Ablation techniques Axillary surgery Timing of surgery Guidelines and choices 18. Treatment options : systemic therapy Chemotherapy Hormone therapy Targeted therapies Second opinions 19. Special cases and populations Locally advanced breast cancer Inflammatory breast cancer The unknown primary Paget's disease of the breast Cystosarcoma phylloides Cancer of both breasts Cancer in the other breast Breast cancer in very young women Breast cancer in elderly women Cancer during pregnancy Breast cancer during lactation Women with implants African American women Beast cancer in men Other cancers 20. Fears, feelings, and ways to cope Weighing the options Finding support Coping : what to tell your children Coping : fears of your loved ones Searching for information What to look for in a doctor and medical team Second opinions pt. 6. Treatment 21. Surgery Anesthesia Preliminary procedures Partial mastectomy and axillary dissection Total mastectomy 22. Reconstruction and prosthesis Prostheses Reconstruction Making a decision The unacceptable reconstruction Partial reconstruction after lumpectomy The other breast 23. Radiation therapy Initial consultation The planning session The treatments The boost Partial breast radiation Side effects 24. Systemic therapy Adjuvant chemotherapy Adjuvant hormone therapy 25. Complementary and alternative treatments Complementary therapies Alternative treatments

pt. 7. Living with breast cancer

26. After treatment

The follow-up

Physical adjustments

Long-term side effects of chemotherapy

Menopausal symptoms

Treatment for symptoms

Lifestyle changes

Healing the mind

Relationships and sex

Pregnancy

Insurance and getting a job

27. When cancer comes back

Local and regional recurrence

Distant recurrence (metastatic disease)

Hormone (endocrine) treatments

Chemotherapy

Targeted therapy

Bisphosphonates

Other treatments

Pain control

Experimental treatments

Taking care of yourself emotionally

When to stop treatment

pt. 8. What is coming

28. The future : from lab to bedside

Tumor stem cells

Gene-environment interaction

Angiogenesis

Translational research

Appendices

A. Drugs used for systemic treatment of breast cancer

B. Resources

C. NCI-designated cancer centers listed by state

D. The wellness community physician/patient statement

E. Pathology checklist

Glossary.